What is Polazi 2 mg (Polmacoxib)?
Polazi 2 mg is a non-steroidal anti-inflammatory drug (NSAID) that is composed of polmacoxib, which was specifically meant to treat osteoarthritis of joints in the knee and hips. Polmacoxib is a non-steroidal anti-inflammatory drug (NSAID) with a greater potency and reduced side effects compared to the conventional ones because it is a dual COX-2 and carbonic anhydrase (CA) inhibitor.
Polazi 2 mg Capsules offer a selective analgesic action for patients with osteoarthritis and a higher safety situation than the usual analgesics. Healing Pharma is the Indian manufacturer of this breakthrough medication.
Polazi 2 mg Capsules Uses
Polazi 2mg Capsules are mainly used in the treatment of osteoarthritis of the knee joint, which gives efficient pain relief and mobility; osteoarthritis of the hip joint, which lowers the inflammation and stiffness; chronic joint pain treatment in patients not responding to conventional NSAIDs; chronic inflammatory joints that need selective COX-2; and long-lasting arthritis treatment with reduced gastrointestinal adverse effects.
The drug is especially helpful in the case of patients who need constant pain management and do not want to interrupt their daily routine and work.
How to take it?
Polazi 2 mg is to be taken as prescribed, with water either with or without food at the same time daily. Do not chew or crush the capsules, and in case you forget to take them, take them when remembered, except when it is nearly time to take the next dose, do not take twice.
How does Polazi 2 mg work?
Polazi 2mg has a dual effect of selectively blocking COX-2 enzymes that produce inflammatory prostaglandins, without blocking stomach-protective COX-1 enzymes, and blocking carbonic anhydrase to reduce tissue acidosis in inflamed joints.
This twofold combination reduces the number of cardiovascular and gastrointestinal side effects and maximizes the effect, which is especially appropriate for patients with concerns of the traditional NSAID complications.
Benefits of Polazi 2 mg
Polazi 2mg Capsules offer significant benefits for osteoarthritis patients:
Physical Benefits:
- Reduced joint pain and stiffness
- Enhanced safety with minimal gastrointestinal toxicity
- Targeted action on inflamed joint tissues
Psychological Benefits:
- Improved quality of life and daily functioning
- Confidence in long-term pain management
- Ability to maintain active lifestyles in Malaysia's climate
Dosage
The standard Polazi 2 mg price reflects its formulation with an adult dosage starting at 2 mg However dosage will be decided by healthcare provider. Elderly patients and those with kidney or liver problems require careful monitoring and potential dose adjustments under medical supervision.
Miss dose
- Take it immediately when remembered
- Skip if it's almost time for the next dose.
- Never double-dose to compensate
Overdose
- Seek immediate medical attention
- Symptoms may include severe dizziness, fainting
Side Effects
While Polazi 2 mg has an improved safety profile, some patients may experience:
Common Side Effects:
- Mild stomach upset or nausea
- Headache or dizziness
- Temporary increase in blood pressure
- Mild skin reactions or rash
- Fluid retention or slight swelling
Serious Side Effects:
- Kidney function changes
- Liver enzyme elevation
- Cardiovascular effects
- Serious allergic reactions (rare)
- Gastrointestinal bleeding (less common than traditional NSAIDs)
Precautions and Warnings
Precautions
- You should tell your doctor about stroke, high blood pressure, heart disease, kidney/liver problems, stomach ulcers, asthma, or blood-clotting disorders.
- It should be used cautiously in patients above 65 years of age.
- May takes blood thinners and heart medications.
- Suggests that the treatment should be monitored regularly to monitor blood pressure and kidney functionality.
- Appropriate medical examination was required prior to initiation of treatment.
Warnings
- Alcohol should be avoided when taking this medicine.
- Should not be used in the third trimester of pregnancy.
- Contraindicated in patients with active stomach ulcers or bleeding disorders.
- Immediately seek medical care in case of chest pain, intense stomach pain, or bleeding.
Where to Buy Polazi 2 mg Online in Malaysia?
Buy Polazi 2 mg at licensed online pharmacies like Malaysiameds.com, It is recommended to consult a doctor before purchasing and have a valid prescription.
Drug Interactions
Medicines that interact with Polazi 2mg:
- Warfarin
- Anticoagulants
- ACE inhibitors
- ARBs (Angiotensin Receptor Blockers)
- Cyclosporine
Conclusion
Polazi 2 mg (polmacoxib) is a major breakthrough in the management of osteoarthritis among Malaysian patients with superior efficacy and safety due to dual mechanism performance unrivalled by the conventional NSAIDs. It is safe with simple once- or twice-daily dosing and has lesser gastrointestinal risks, as well as being highly effective in long-term treatment of joint pain with minimal adverse effects of NSAIDs. Always consult qualified Malaysian healthcare professionals to find out whether Polazi 2mg suits you or not.
Frequently Asked Questions (FAQs)
Can I take Polazi if I have heart problems?
Should be used with careful supervision by cardiac observation because Polazi 2mg may influence heart rate as well as blood pressure.
Can Polazi 2 mg be taken during pregnancy or breastfeeding?
Contraindicated in pregnancy or when breastfeeding since Polazi 2mg can result in complications in the foetus and be transmitted through the breast milk.
Can I take Polazi with alcohol?
Alcohol must be avoided at all costs because it puts risks of bleeding, liver restrictions, and kidney issues with Polazi 2mg.
Is Polazi safe for long-term use?
Yes, but it requires monitoring of kidney and liver function and blood pressure every 3-6 months.
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