Lithium Carbonate Prolonged Release 450 mg (Generic)

What is Lithium Carbonate Prolonged Release 450 mg?

Lithium Carbonate Prolonged Release 450 mg is a specialised medication formulated to manage mood disorders such as mania and bipolar disorder. Produced by Intas Pharmaceuticals Ltd, this prolonged release formulation ensures a steady release of lithium carbonate into the bloodstream, providing effective and sustained control over symptoms. It is widely recognised and prescribed in Malaysia for its efficacy and safety profile when used under medical supervision.

Lithium carbonate, the active ingredient in this product, has been extensively studied and used in psychiatry for decades. Its prolonged release form helps minimise fluctuations in blood lithium levels, thereby reducing side effects and improving patient compliance. This tablet is designed for those who require consistent therapeutic action over an extended period.

This medicine is essential in stabilising mood swings, preventing both manic and depressive episodes. Its use forms a cornerstone in the maintenance therapy of bipolar disorder, helping patients lead a balanced and functional life. The prolonged release mechanism also aids in reducing the frequency of dosing, making it convenient for daily use.

Uses of Lithium Carbonate Prolonged Release 450 mg

• Management of acute mania in bipolar disorder
• Maintenance treatment to prevent recurrence of bipolar mood episodes
• Stabilisation of mood swings associated with bipolar disorder
• Adjunct therapy in controlling resistant cases of mania

How Lithium Carbonate Prolonged Release 450 mg Works

Lithium carbonate acts on the central nervous system to modulate the transmission of nerve signals. It is believed to influence neurotransmitters such as serotonin and dopamine, which regulate mood and behavior. By altering these chemical processes, Lithium Carbonate Prolonged Release 450 mg helps reduce the severity and frequency of manic episodes and stabilises mood fluctuations.

The prolonged release formulation ensures that lithium ion levels remain stable in the bloodstream over a 12- to 24-hour period. This steady-state release prevents peaks and troughs that can lead to toxicity or reduced efficacy, allowing for smoother symptom control and improved patient safety.

How to take Lithium Carbonate Prolonged Release 450 mg

Take the tablets exactly as prescribed by your healthcare provider. Typically, the tablet should be swallowed whole with a full glass of water. Do not crush, chew, or break the tablet as this will affect the prolonged release mechanism.

It is recommended to take the medicine at the same time(s) each day to maintain consistent blood levels. Follow your doctor’s dosage instructions carefully and do not adjust your dose without consulting them. Regular blood tests may be required to monitor lithium levels and kidney function during treatment.

Benefits of Lithium Carbonate Prolonged Release 450 mg

• Effective control of manic episodes in bipolar disorder
• Helps maintain mood stability over the long term
• Prolonged release ensures steady therapeutic lithium levels
• Reduces frequency of dosing and improves patient compliance
• Manufactured by a reputable pharmaceutical company ensuring quality

Dosage and Administration

Dosage is individualised based on patient’s condition, response, and blood lithium levels. The typical starting dose ranges between 450 mg to 900 mg daily, which may be adjusted by your physician. Tablets are often taken once or twice daily due to the prolonged release nature.

Regular monitoring of lithium plasma concentration is essential to avoid toxicity. Never take more or less than the prescribed dose. Inform your doctor if you experience any unusual symptoms or side effects.

Who Should Use Lithium Carbonate Prolonged Release 450 mg?

This medication is intended for adults diagnosed with bipolar disorder or mania who require mood stabilisation. Patients under psychiatric care who have had recurrent manic episodes or those in maintenance therapy to prevent relapse can benefit from this treatment.

It should be used under strict medical guidance, especially in patients with a history of mental health disorders, to ensure safe and effective use.

Who Should Avoid Lithium Carbonate Prolonged Release 450 mg?

Patients with significant kidney disease or impaired renal function should avoid this medicine. It is contraindicated in individuals with known hypersensitivity to lithium or any component of the tablet.

Pregnant and breastfeeding women should consult their healthcare provider before use, as lithium can affect the fetus and infant. Patients with severe cardiovascular disease or dehydration should also avoid lithium usage unless closely monitored.

Side Effects of Lithium Carbonate Prolonged Release 450 mg

• Tremors or shaking hands
• Increased thirst
• Frequent urination
• Diarrhoea or nausea
• Weight gain
• Dry mouth
• Fatigue or tiredness
• Muscle weakness
• Blurred vision
• Difficulty concentrating
• Skin rash or itching
• Swelling of the hands or feet

Safety Advice

• Always follow the prescribed dose and schedule
• Do not stop treatment abruptly without consulting your doctor
• Maintain adequate hydration to reduce risk of lithium toxicity
• Avoid activities requiring alertness if dizziness occurs
• Notify your doctor immediately if you experience signs of overdose such as severe tremors, confusion, or irregular heartbeat
• Regularly monitor kidney function and lithium blood levels as advised
• Inform your healthcare provider of all other medicines you are taking

Drug Interactions

• Diuretics (can increase lithium levels)
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• ACE inhibitors and angiotensin receptor blockers
• Antidepressants and antipsychotics
• Drugs affecting kidney function

Storage Instructions

Store Lithium Carbonate Prolonged Release 450 mg tablets in a cool, dry place away from direct sunlight and moisture. Keep the medicine out of reach of children. Avoid storing in the bathroom or damp areas. Check the expiry date before use and do not consume expired medication.

Where to buy Lithium Carbonate Prolonged Release 450 mg in Malaysia?

In Malaysia, Lithium Carbonate Prolonged Release 450 mg can be purchased at licensed pharmacies and through reputable online drugstores with a valid prescription. Always ensure you buy from authorised sellers to guarantee genuine product quality. Consult your healthcare provider for guidance on obtaining this medication safely.

Frequently Asked Questions (FAQ)

What is the price of Lithium Carbonate Prolonged Release 450 mg in Malaysia?

The price varies depending on the pharmacy and supplier, but it generally remains affordable. Check with local or online pharmacies for current pricing and possible insurance coverage.

What happens if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose. Do not double the dose to catch up. Consult your doctor if you often forget doses.

Where can I find Lithium Carbonate Prolonged Release 450 mg for sale?

This medicine is available at licensed pharmacies across Malaysia and through authorised online medicine providers. Always purchase with a prescription to ensure safety and authenticity.

Is Lithium Carbonate Prolonged Release 450 mg available in Malaysia?

Yes, it is widely available and commonly prescribed by psychiatrists for managing bipolar disorder and mania in Malaysia.

Can I drink alcohol while taking Lithium Carbonate Prolonged Release 450 mg?

It is advisable to avoid alcohol while on lithium therapy as it can increase side effects and affect medication levels.

How long does it take for Lithium Carbonate Prolonged Release 450 mg to work?

Improvement in mood symptoms may take several days to weeks. Consistent use as prescribed is important for optimal results.

Can I use Lithium Carbonate Prolonged Release 450 mg during pregnancy?

Use during pregnancy requires careful medical evaluation due to potential risks to the fetus. Always consult your doctor beforehand.

Conclusion

Lithium Carbonate Prolonged Release 450 mg is a proven and effective treatment option for managing mania and bipolar disorder. Its prolonged release formulation enhances patient compliance and maintains stable therapeutic levels, contributing to better mood stabilization. Manufactured by Intas Pharmaceuticals Ltd, it offers a reliable solution for those in need of long-term mood management. Always use under medical supervision to ensure safety and optimal benefits.